- Ph.D., University of Oxford, 1989
- B.S., University of Otago, New Zealand, 1984
Honors and Awards
- Fellow The Royal Society (elected 2015)
- Fellow American Academy of Microbiology (elected 2014)
- Fellow of American Association for the Advancement of Science (elected 2012)
- Fellowship Wissenschaftskolleg zu Berlin, 2006-2007
- Fellow of Royal Society of Edinburgh (elected 2003)
- Scientific Medal, Zoological Society of London, 1999
- Young Investigator Award, American Society of Naturalists, 1991
- Thomas Henry Huxley Award, Zoological Society of London, 1991
We work on the ecology and evolution of infectious disease. We exploit modern notions of adaptive evolution to attack biomedically and theoretically challenging phenomena like virulence and infectiousness, adaptation to new hosts, vaccine escape, and drug and insecticide resistance. Our work involves evolutionary biology, ecology, parasitology, microbiology, genetics, and immunology. Currently, much of the work concerns the three players that cause malaria (the parasite, the vertebrate host, and the mosquito), as well entomopathogenic fungi and Marek’s disease of chickens. In the past, we also have worked on the parasites of Daphnia, African trypanosomes, and parasitic nematodes of mammals.
Day, T., & Read A.F. (2016). When does high-dose antimicrobial chemotherapy prevent the emergence of resistance? PLoS Computational Biology 12: e1004689.
Read, A.F., Baigent, S.J., Powers, C., Kgosana, L.B., Blackwell, L., Smith, L.P., Kennedy, D.A., Walkden-Brown, S.W., & Nair, V.K. 2015. Vaccination enhances transmission of highly virulent strains of Marek’s disease virus in chickens. PLoS Biology 13: e1002198.
Huijben, S., Bell, A.S., Sim, D.G., Salathe, R., Tomasello, D., Mideo, N., Day, T. & Read, A.F. 2013. Aggressive chemotherapy and the selection of drug resistant pathogens. PLoS Pathogens 9: e1003578.
Barclay, V.C., Sim, D., Chan, B.H.K., Nell, L.A., Rabaa, M.A., Bell, A.S., Anders, R.F. & Read, A.F. 2012. The evolutionary consequences of blood-stage vaccination on the rodent malaria Plasmodium chabaudi. PLoS Biology 10: e1001368.
Read, A. F., T. Day, and S. Huijben. 2011. The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy. Proceedings of the National Academy of Sciences USA 108: 10871.
Read, A. F., P. A. Lynch, and M. B. Thomas. 2009. How to build an evolution-proof insecticide for malaria control. PLoS Biology 7: e1000058.
Råberg, L., D. Sim, and A. F. Read. 2007. Disentangling genetic variation for resistance and tolerance to infectious diseases in animals. Science 318: 812.
Blanford, S., B. H. Chan, N. Jenkins, D. Sim, R. J. Turner, A. F. Read, M. B. Thomas. 2005. Fungal pathogen reduces potential for malaria transmission. Science 308: 1638.